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Blood vessel imaging using radiofrequency-induced second harmonic acoustic response.

ABSTRACT: We introduce a contrast mechanism for visualizing blood vessels based on radiofrequency-induced second harmonic acoustic (RISHA) signals sensing blood conductivity. We develop a novel imaging system using commonly available inexpensive components, and demonstrate in vivo RISHA visualization of blood vessels based on low-power quasi-continuous radiofrequency excitation of tissue at frequencies of a few MHz. We show how the novel approach also implicitly enables radiofrequency-induced passive ultrasound imaging and can be readily applied to non-invasive imaging of blood vessels ex vivo and in vivo. We discuss the implications of non-invasive conductivity measurements in the context of biomedical applications.

SUBMITTER: Huang Y

PROVIDER: S-EPMC6195590 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Blood vessel imaging using radiofrequency-induced second harmonic acoustic response.

Huang Yuanhui Y Kellnberger Stephan S Sergiadis George G Ntziachristos Vasilis V

Scientific reports 20181019 1

We introduce a contrast mechanism for visualizing blood vessels based on radiofrequency-induced second harmonic acoustic (RISHA) signals sensing blood conductivity. We develop a novel imaging system using commonly available inexpensive components, and demonstrate in vivo RISHA visualization of blood vessels based on low-power quasi-continuous radiofrequency excitation of tissue at frequencies of a few MHz. We show how the novel approach also implicitly enables radiofrequency-induced passive ultr ...[more]

PMID: 30341349

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