Ontology highlight
ABSTRACT:
SUBMITTER: Lopez-Moya M
PROVIDER: S-EPMC6198652 | biostudies-literature | 2018 Apr
REPOSITORIES: biostudies-literature
Lopez-Moya Mario M Melgar-Lesmes Pedro P Kolandaivelu Kumaran K de la Torre Hernández Jose María JM Edelman Elazer R ER Balcells Mercedes M
Biomacromolecules 20180320 4
Porcine glutaraldehyde-fixed pericardium is widely used to replace human heart valves. Despite the stabilizing effects of glutaraldehyde fixation, the lack of endothelialization and the occurrence of immune reactions contribute to calcification and structural valve deterioration, which is particularly significant in young patients, in whom valve longevity is crucial. This report shows an optimization system with which to enhance endothelialization of fixed pericardium to mimic the biological fun ...[more]