SAC3D1: a novel prognostic marker in hepatocellular carcinoma.
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ABSTRACT:
SUBMITTER: Han ME
PROVIDER: S-EPMC6199250 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Publications
SAC3D1: a novel prognostic marker in hepatocellular carcinoma.
Han Myoung-Eun ME Kim Ji-Young JY Kim Ga Hyun GH Park Si Young SY Kim Yun Hak YH Oh Sae-Ock SO
Scientific reports 20181023 1
Centrosome-associated proteins are recognized as prognostic factors in many cancers because centrosomes are critical structures for the cell cycle progression and genomic stability. SAC3D1, however, is associated with centrosome abnormality, although its prognostic potential has not been evaluated in hepatocellular carcinoma (HCC). In this study, 3 independent cohorts (GSE10186, n = 80; TCGA, n = 330 and ICGC, n = 237) were used to assess SAC3D1 as a biomarker, which demonstrated SAC3D1 overexpr ...[more]
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