Ontology highlight
ABSTRACT:
SUBMITTER: Sakaguchi M
PROVIDER: S-EPMC6199656 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Sakaguchi Masahiro M Yamaguchi Hiroki H Najima Yuho Y Usuki Kensuke K Ueki Toshimitsu T Oh Iekuni I Mori Sinichiro S Kawata Eri E Uoshima Nobuhiko N Kobayashi Yutaka Y Kako Shinichi S Tajika Kenji K Gomi Seiji S Shono Katsuhiro K Kayamori Kensuke K Hagihara Masao M Kanda Junya J Uchiyama Hitoji H Kuroda Junya J Uchida Naoyuki N Kubota Yasushi Y Kimura Shinya S Kurosawa Saiko S Nakajima Nana N Marumo Atsushi A Omori Ikuko I Fujiwara Yusuke Y Yui Shunsuke S Wakita Satoshi S Arai Kunihito K Kitano Tomoaki T Kakihana Kazuhiko K Kanda Yoshinobu Y Ohashi Kazuteru K Fukuda Takahiro T Inokuchi Koiti K
Blood advances 20181001 20
In the opinion of the European LeukemiaNet (ELN), nucleophosmin member 1 gene mutation (<i>NPM1</i> mut)-positive acute myeloid leukemia (AML) with an fms-like kinase 3-internal tandem duplication (<i>FLT3</i>-ITD) allele ratio (AR) <0.5 (low AR) has a favorable prognosis, and allogeneic hematopoietic stem cell transplant (allo-HSCT) in the first complete remission (CR1) period is not actively recommended. We studied 147 patients with <i>FLT3</i>-ITD gene mutation-positive AML, dividing them int ...[more]