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Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018.

ABSTRACT: Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical products during manufacturing may lead to international outbreaks.

SUBMITTER: Becker SL

PROVIDER: S-EPMC6199865 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Outbreak of Burkholderia cepacia complex infections associated with contaminated octenidine mouthwash solution, Germany, August to September 2018.

Becker Sören L SL Berger Fabian K FK Feldner Susanne K SK Karliova Irem I Haber Manfred M Mellmann Alexander A Schäfers Hans-Joachim HJ Gärtner Barbara B

Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin 20181001 42

Three German patients developed nosocomial pneumonia after cardiac surgery and had Burkholderia cepacia complex detected in respiratory specimens. Two patients died of septic multi-organ failure. Whole-genome sequencing detected genetically identical B. cepacia complex strains in patient samples, from a batch of octenidine mouthwash solution, which had been used for nursing care, as well as in samples obtained from the manufacturer during production. Contamination of medical produc ...[more]

PMID: 30352639

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