Ontology highlight
ABSTRACT:
SUBMITTER: Rosanova M
PROVIDER: S-EPMC6200777 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Nature communications 20181024 1
Unresponsive wakefulness syndrome (UWS) patients may retain intact portions of the thalamocortical system that are spontaneously active and reactive to sensory stimuli but fail to engage in complex causal interactions, resulting in loss of consciousness. Here, we show that loss of brain complexity after severe injuries is due to a pathological tendency of cortical circuits to fall into silence (OFF-period) upon receiving an input, a behavior typically observed during sleep. Spectral and phase do ...[more]