Unknown

Dataset Information

0

Relation between opioid-related harms and socioeconomic inequalities in Ontario: a population-based descriptive study.


ABSTRACT:

Background

Negative health outcomes associated with the use of both prescribed and nonprescribed opioids are increasingly prevalent. We examined long-term trends in opioid-related harms in Ontario across a set of 6 indicators and the relation between harms and neighbourhood income in 2016.

Methods

We examined rates of neonatal abstinence syndrome, opioid poisoning (fatal and nonfatal) and nonpoisoning opioid-related events from 2003 to 2016 in Ontario using population-based health administrative databases. We conducted descriptive analyses for harm indicators across neighbourhood income quintiles in 2016 (2015 for death). We examined social inequalities in opioid-related harms on both relative (prevalence ratio) and absolute (potential rate reduction) scales.

Results

Rates of opioid-related harms increased dramatically between 2003 and 2016. In 2016, neonatal abstinence syndrome and opioid poisoning and nonpoisoning events showed a strong social gradient, with harm rates being lowest in higher-income neighbourhoods and highest in lower-income neighbourhoods. Prevalence ratios for the lowest-income neighbourhoods compared to the highest-income neighbourhoods ranged from 2.36 (95% confidence interval [CI] 2.15-2.58) for emergency department visits for opioid poisoning to 3.70 (95% CI 2.62-5.23) for neonatal abstinence syndrome. Potential rate reductions for opioid-related harms ranged from 34.8% (95% CI 29.1-40.1) to 49.9% (95% CI 36.7-60.5), which suggests that at least one-third of all harmful events could be prevented if all neighbourhoods had the same socioeconomic profile as the highest-income neighbourhoods.

Interpretation

Rates of opioid-related harms increased in Ontario between 2003 and 2016, and people in lower-income neighbourhoods experienced substantially higher rates of opioid-related harms than those in higher-income neighbourhoods. This finding can inform planning for opioid-related public health interventions with consideration of health equity.

SUBMITTER: Cairncross ZF 

PROVIDER: S-EPMC6201733 | biostudies-literature | 2018 Oct-Dec

REPOSITORIES: biostudies-literature

altmetric image

Publications

Relation between opioid-related harms and socioeconomic inequalities in Ontario: a population-based descriptive study.

Cairncross Zoe F ZF   Herring Jeremy J   van Ingen Trevor T   Smith Brendan T BT   Leece Pamela P   Schwartz Brian B   Hohenadel Karin K  

CMAJ open 20181018 4


<h4>Background</h4>Negative health outcomes associated with the use of both prescribed and nonprescribed opioids are increasingly prevalent. We examined long-term trends in opioid-related harms in Ontario across a set of 6 indicators and the relation between harms and neighbourhood income in 2016.<h4>Methods</h4>We examined rates of neonatal abstinence syndrome, opioid poisoning (fatal and nonfatal) and nonpoisoning opioid-related events from 2003 to 2016 in Ontario using population-based health  ...[more]

Similar Datasets

| S-EPMC10267543 | biostudies-literature
| S-EPMC9099533 | biostudies-literature
| S-EPMC7117737 | biostudies-literature
| S-EPMC9929598 | biostudies-literature
| S-EPMC5621958 | biostudies-literature
| S-EPMC6113771 | biostudies-literature
| S-EPMC7082105 | biostudies-literature
| S-EPMC7313902 | biostudies-literature
| S-EPMC8288297 | biostudies-literature
| S-EPMC6972194 | biostudies-literature