Ontology highlight
ABSTRACT:
SUBMITTER: Maas H
PROVIDER: S-EPMC6202931 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Maas Hugo H Gropper Savion S Huang Fenglei F Stangier Joachim J Tartakovsky Igor I Brueckmann Martina M Halton Jacqueline M L JML Mitchell Lesley G LG
Thrombosis and haemostasis 20180815 9
<h4>Background</h4> Physiological age-related changes in the haemostatic and coagulation systems result in differing anticoagulant assay responses to standard anticoagulants. Therefore, we investigated the response of anticoagulant assays to dabigatran etexilate (DE) in children compared with adults.<h4>Objective</h4> This article assesses the relationship between plasma dabigatran concentration and coagulation assay results across age groups in children and adults.<h4>Patients and methods</h4> ...[more]