Ontology highlight
ABSTRACT: Background
A population-based study of Chlamydia trachomatis (CT) infections is essential in designing a specific control program; however, no large investigation of CT infections among the general population in mainland China has been conducted since 2000. We aimed to determine the prevalence, risk factors, and associated medical costs of CT among residents, 18-49 years of age, in Shandong, China.Methods
From May to August 2016, a multistage probability sampling survey involving 8074 individuals was distributed. Data were collected via face-to-face interviews, followed by self-administered questionnaire surveys. First-void urines were collected and tested for CT and Neisseria gonorrhoeae (NG) using nucleic acid amplification.Results
The weighted prevalence of CT infection was 2.3% (95% confidence interval [CI], 1.5-3.2) in females and 2.7% (1.6-3.8) in males. Women, 30-34 years of age, had the highest prevalence of CT infections (3.5%, 2.6-4.4), while the highest prevalence of CT infections in males was in those 18-24 years of age (4.3%, 0.0-8.8). Neisseria gonorrhoeae infection had a prevalence of 0.1% (0.0-0.3) in women and 0.03% (0.0-0.1) in men. Risk factors for CT infections among females included being unmarried, divorced, or widowed (odds ratio [OR], 95% CI 3.57, 1.54-8.24) and having two or more lifetime sex partners (3.72, 1.14-12.16). Among males, first intercourse before 20 years of age (1.83, 1.10-3.02) and having two or more lifetime sex partners (1.85, 1.14-3.02) were associated with CT infections. The estimated lifetime cost of CT infections in patients 18-49 years of age in Shandong was 273 million (range, 172-374 million) China Renminbi in 2016.Conclusions
This study demonstrated a high burden of CT infections among females
SUBMITTER: Huai P
PROVIDER: S-EPMC6204023 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Huai Pengcheng P Li Furong F Li Zhen Z Sun Lele L Fu Xi'an X Pan Qing Q Yu Gongqi G Chai Zemin Z Chu Tongsheng T Mi Zihao Z Bao Fangfang F Wang Honglei H Zhou Bingni B Wang Chuan C Sun Yonghu Y Niu Guiye G Zhang Yuan Y Fu Fanghui F Lang Xiaoqiao X Wang Xiaoling X Zhao Hui H Liu Daina D Liu Hong H Liu Dianchang D Liu Jian J Xu Aiqiang A Zhang Furen F
BMC infectious diseases 20181026 1
<h4>Background</h4>A population-based study of Chlamydia trachomatis (CT) infections is essential in designing a specific control program; however, no large investigation of CT infections among the general population in mainland China has been conducted since 2000. We aimed to determine the prevalence, risk factors, and associated medical costs of CT among residents, 18-49 years of age, in Shandong, China.<h4>Methods</h4>From May to August 2016, a multistage probability sampling survey involving ...[more]