Evaluating quantitative proton-density-mapping methods.
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ABSTRACT:
SUBMITTER: Mezer A
PROVIDER: S-EPMC6204063 | biostudies-literature | 2016 Oct
REPOSITORIES: biostudies-literature
Publications
Evaluating quantitative proton-density-mapping methods.
Mezer Aviv A Rokem Ariel A Berman Shai S Hastie Trevor T Wandell Brian A BA
Human brain mapping 20160606 10
Quantitative magnetic resonance imaging (qMRI) aims to quantify tissue parameters by eliminating instrumental bias. We describe qMRI theory, simulations, and software designed to estimate proton density (PD), the apparent local concentration of water protons in the living human brain. First, we show that, in the absence of noise, multichannel coil data contain enough information to separate PD and coil sensitivity, a limiting instrumental bias. Second, we show that, in the presence of noise, reg ...[more]
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