Ontology highlight
ABSTRACT:
SUBMITTER: Ditlev JA
PROVIDER: S-EPMC6204295 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Ditlev Jonathon A JA Case Lindsay B LB Rosen Michael K MK
Journal of molecular biology 20180809 23
Biomolecular condensates are two- and three-dimensional compartments in eukaryotic cells that concentrate specific collections of molecules without an encapsulating membrane. Many condensates behave as dynamic liquids and appear to form through liquid-liquid phase separation driven by weak, multivalent interactions between macromolecules. In this review, we discuss current models and data regarding the control of condensate composition, and we describe our current understanding of the compositio ...[more]