Ontology highlight
ABSTRACT:
SUBMITTER: Mishra AP
PROVIDER: S-EPMC6204428 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Mishra Arun Prakash AP Yedella Komala K Lakshmi Jyothi B JB Siva Archana B AB
Nutrition & diabetes 20181029 1
Type I diabetes, though contributes to only 5-10% of total diabetes cases, is a rising concern in today's world. Our previous studies have shown that the absence of WDR13 in mouse results in pancreatic β-cell hyper-proliferation. Also, amelioration of the diabetic phenotype on introgression of Wdr13-null (Wdr13<sup>-/0</sup>) mutation in genetically diabetic mice (Lepr<sup>db/db</sup>) [type II diabetes] was observed. It was thus, interesting to see the role of WDR13 in streptozotocin-mediated d ...[more]