ESM-CT: a precise method for localization of DBS electrodes in CT images.

ABSTRACT:

Background

Deep brain stimulation (DBS) of the subthalamic nucleus produces variable effects in Parkinson disease. Variation may result from different electrode positions relative to target. Thus, precise electrode localization is crucial when investigating DBS effects.

New method

We developed a semi-automated method, Electrode Shaft Modeling in CT images (ESM-CT) to reconstruct DBS lead trajectories and contact locations. We evaluated methodological sensitivity to operator-dependent steps, robustness to image resampling, and test-retest replicability. ESM-CT was applied in 56 patients to study electrode position change (and relation to time between scans, postoperative subdural air volume, and head tilt during acquisition) between images acquired immediately post-implantati

SUBMITTER: Milchenko M 

PROVIDER: S-EPMC6205293 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature