Ontology highlight
ABSTRACT:
SUBMITTER: Milchenko M
PROVIDER: S-EPMC6205293 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Milchenko Mikhail M Snyder Abraham Z AZ Campbell Meghan C MC Dowling Joshua L JL Rich Keith M KM Brier Lindsey M LM Perlmutter Joel S JS Norris Scott A SA
Journal of neuroscience methods 20180907
<h4>Background</h4>Deep brain stimulation (DBS) of the subthalamic nucleus produces variable effects in Parkinson disease. Variation may result from different electrode positions relative to target. Thus, precise electrode localization is crucial when investigating DBS effects.<h4>New method</h4>We developed a semi-automated method, Electrode Shaft Modeling in CT images (ESM-CT) to reconstruct DBS lead trajectories and contact locations. We evaluated methodological sensitivity to operator-depend ...[more]