Ontology highlight
ABSTRACT:
SUBMITTER: Yu Y
PROVIDER: S-EPMC6205330 | biostudies-literature | 2018 Dec
REPOSITORIES: biostudies-literature
Yu Yang Y Zhang Mingjiong M Liu Jie J Xu Boming B Yang Jian J Wang Ni N Yan Shuai S Wang Fei F He Xuezhi X Ji Guozhong G Li Quanpeng Q Miao Lin L
Molecular therapy. Nucleic acids 20181010
Cholangiocarcinoma (CCA) is the most common biliary tract malignancy, with a low survival rate and limited treatment options. Long non-coding RNAs (lncRNAs) have recently been verified to have significant regulatory functions in many kinds of human cancers. It was discovered in this study that the lncRNA PVT1, whose expression is significantly elevated in CCA, could be a molecular marker of CCA. Experiments indicated that PVT1 knockdown greatly inhibited cell migration and proliferation in vitro ...[more]