EUS-guided portal pressure gradient measurement with a simple novel device: a human pilot study.

ABSTRACT:

Background and aims

Portal hypertension is a serious adverse event of liver cirrhosis. Recently, we developed a simple novel technique for EUS-guided portal pressure gradient (PPG) measurement (PPGM). Our animal studies showed excellent correlation between EUS-PPGM and interventional radiology-acquired PPGM. In this video we demonstrate the results of the first human pilot study of EUS-PPGM in patients with liver disease.

Methods

EUS-PPGM was performed by experienced endosonographers using a linear echoendoscope, a 25-gauge FNA needle, and a novel compact manometer. The portal vein and hepatic vein (or inferior vena cava) were targeted by use of a transgastric or transduodenal approach. Feasibility was defined as successful PPGM in each patient. Safety was based on adverse e

SUBMITTER: Samarasena JB 

PROVIDER: S-EPMC6205538 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature