Ontology highlight
ABSTRACT:
SUBMITTER: Lam MMC
PROVIDER: S-EPMC6205773 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Lam Margaret M C MMC Wyres Kelly L KL Judd Louise M LM Wick Ryan R RR Jenney Adam A Brisse Sylvain S Holt Kathryn E KE
Genome medicine 20181029 1
<h4>Background</h4>Klebsiella pneumoniae is a recognised agent of multidrug-resistant (MDR) healthcare-associated infections; however, individual strains vary in their virulence potential due to the presence of mobile accessory genes. In particular, gene clusters encoding the biosynthesis of siderophores aerobactin (iuc) and salmochelin (iro) are associated with invasive disease and are common amongst hypervirulent K. pneumoniae clones that cause severe community-associated infections such as li ...[more]