Dataset Information

Cigarette smoking and risk of celiac disease: A systematic review and meta-analysis.

ABSTRACT:

Background/objectives

A negative association between cigarette smoking and celiac disease has been observed but results were inconsistent across the published studies. A meta-analysis was conducted with the aim to identify all studies that investigated this association and to summarize the results of those studies.

Methods

A comprehensive literature review was conducted utilizing MEDLINE and Embase databases through March 2018 to identify all cohort studies and case-control studies that compared the risk of celiac disease among current and/or former smokers versus never-smokers. Effect estimates from each study were extracted and combined together using the random-effect, generic inverse variance method of DerSimonian and Laird.

Results

A total of seven studies with 307,924 participants fulfilled the eligibility criteria and were included in the meta-analysis. The pooled analysis found a significantly decreased risk of celiac disease among current smokers compared with never-smokers with the pooled odds ratio (OR) of 0.52 (95% confidence interval (CI), 0.32-0.84; I² 86%). However, the risk of celiac disease among former smokers was not significantly different from never-smokers with the pooled OR of 1.10 (95% CI, 0.76-1.60; I² of 73%).

Conclusions

A significantly decreased risk of celiac disease among current smokers compared with never-smokers was demonstrated in this meta-analysis.

SUBMITTER: Wijarnpreecha K

PROVIDER: S-EPMC6206527 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Publications

Cigarette smoking and risk of celiac disease: A systematic review and meta-analysis.

Wijarnpreecha Karn K Lou Susan S Panjawatanan Panadeekarn P Cheungpasitporn Wisit W Pungpapong Surakit S Lukens Frank J FJ Ungprasert Patompong P

United European gastroenterology journal 20180627 9

<h4>Background/objectives</h4>A negative association between cigarette smoking and celiac disease has been observed but results were inconsistent across the published studies. A meta-analysis was conducted with the aim to identify all studies that investigated this association and to summarize the results of those studies.<h4>Methods</h4>A comprehensive literature review was conducted utilizing MEDLINE and Embase databases through March 2018 to identify all cohort studies and case-control studie ...[more]

PMID: 30386601

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Dataset Information

Cigarette smoking and risk of celiac disease: A systematic review and meta-analysis.

Background/objectives

Methods

Results

Conclusions

Publications

Cigarette smoking and risk of celiac disease: A systematic review and meta-analysis.

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