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Prophylactic potential of a Panchgavya formulation against certain pathogenic bacteria.


ABSTRACT: A Panchgavya preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm Caenorhabditis elegans as a model host. Worms fed with the Panchgavya preparation prior to being challenged with pathogenic bacteria had a better survival rate against four out of five test bacterial pathogens, as compared to the control worms. Panchgavya feeding prior to bacterial challenge was found to be most effective against Staphylococcus aureus, resulting in 27% (p=0.0001) better worm survival. To the best of our awareness, this is the first report demonstrating in vivo prophylactic efficacy of Panchgavya mixture against pathogenic bacteria.

SUBMITTER: Patel P 

PROVIDER: S-EPMC6206607 | biostudies-literature | 2018

REPOSITORIES: biostudies-literature

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Prophylactic potential of a <i>Panchgavya</i> formulation against certain pathogenic bacteria.

Patel Pooja P   Joshi Chinmayi C   Funde Snehal S   Palep Hanumanthrao H   Kothari Vijay V  

F1000Research 20181008


A <i>Panchgavya</i> preparation was evaluated for its prophylactic efficacy against bacterial infection, employing the nematode worm <i>Caenorhabditis elegans</i> as a model host. Worms fed with the <i>Panchgavya</i> preparation prior to being challenged with pathogenic bacteria had a better survival rate against four out of five test bacterial pathogens, as compared to the control worms. <i>Panchgavya</i> feeding prior to bacterial challenge was found to be most effective against <i>Staphylococ  ...[more]

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