Immune phenotype of peripheral blood mononuclear cells in patients with high-risk non-muscle invasive bladder cancer.
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ABSTRACT:
SUBMITTER: Audenet F
PROVIDER: S-EPMC6207464 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Immune phenotype of peripheral blood mononuclear cells in patients with high-risk non-muscle invasive bladder cancer.
Audenet François F Farkas Adam M AM Anastos Harry H Galsky Matthew D MD Bhardwaj Nina N Sfakianos John P JP
World journal of urology 20180602 11
<h4>Purpose</h4>To explore the immune phenotype of peripheral blood mononuclear cells (PBMC) in patients with high-risk non-muscle invasive bladder cancer (NMIBC).<h4>Methods</h4>We prospectively collected blood samples from patients with high-risk NMIBC treated at our institution. PBMC were analyzed by flow cytometry to determine the frequency of T cells and NK cells and the expression of immunoregulatory molecules (Tim-3, TIGIT and PD-1). PBMC from healthy donors (HD) were included for compari ...[more]
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