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Prognostic Influence of Preoperative Mammographic Breast Density in Operable Invasive Female Breast Cancer.


ABSTRACT: We aimed to investigate the potential of preoperative mammographic breast density (MBD) as a prognostic factor in breast cancer. Data of 969 patients with primary breast cancer were analyzed. We defined low MBD as fatty or fibroglandular breast, and high MBD as heterogeneously dense or extremely dense breast, respectively. The high MBD group demonstrated a superior overall survival rate compared to the low MBD group (p?50 years (p?2 (p?50 years and the HRc(+)/HER2(-) subtype. Favorable clinicopathologic features, active treatments, and other factors could contribute to this causality.

SUBMITTER: Hwang KT 

PROVIDER: S-EPMC6207781 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Prognostic Influence of Preoperative Mammographic Breast Density in Operable Invasive Female Breast Cancer.

Hwang Ki-Tae KT   Chu A Jung AJ   Kim Jongjin J   Lee Jong Yoon JY   Chang Ji Hyun JH   Oh Sohee S   Kim Young A YA   Jung Jiwoong J   Oh Bumjo B  

Scientific reports 20181030 1


We aimed to investigate the potential of preoperative mammographic breast density (MBD) as a prognostic factor in breast cancer. Data of 969 patients with primary breast cancer were analyzed. We defined low MBD as fatty or fibroglandular breast, and high MBD as heterogeneously dense or extremely dense breast, respectively. The high MBD group demonstrated a superior overall survival rate compared to the low MBD group (p < 0.001). Favorable prognostic effects of high MBD were observed in subgroups  ...[more]

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