Ontology highlight
ABSTRACT:
SUBMITTER: Navarro-Sanchez L
PROVIDER: S-EPMC6210421 | biostudies-literature | 2018 Sep
REPOSITORIES: biostudies-literature
Navarro-Sánchez Luis L Águeda-Gómez Beatriz B Aparicio Silvia S Pérez-Tur Jordi J
Cells 20180926 10
Efforts have been made to understand the pathophysiology of Parkinson's disease (PD). A significant number of studies have focused on genetics, despite the fact that the described pathogenic mutations have been observed only in around 10% of patients; this observation supports the fact that PD is a multifactorial disorder. Lately, differences in miRNA expression, histone modification, and DNA methylation levels have been described, highlighting the importance of epigenetic factors in PD etiology ...[more]