Ontology highlight
ABSTRACT:
SUBMITTER: Greengard EG
PROVIDER: S-EPMC6210520 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Children (Basel, Switzerland) 20181015 10
Neuroblastoma is the most common extra-cranial solid tumor encountered in childhood and accounts for 15% of pediatric cancer-related deaths. Although there has been significant improvement in the outcomes for patients with high-risk disease, the therapy needed to achieve a cure is quite toxic and for those that do experience a disease recurrence, the prognosis is very dismal. Given this, there is a tremendous need for novel therapies for children with high-risk neuroblastoma and the molecular di ...[more]