Ontology highlight
ABSTRACT:
SUBMITTER: Takahashi T
PROVIDER: S-EPMC6210652 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Takahashi Tomoko T Nakano Yuko Y Onomoto Koji K Yoneyama Mitsutoshi M Ui-Tei Kumiko K
Genes 20181019 10
Exogenous double-stranded RNAs (dsRNAs) similar to viral RNAs induce antiviral RNA silencing or RNA interference (RNAi) in plants or invertebrates, whereas interferon (IFN) response is induced through activation of virus sensor proteins including Toll like receptor 3 (TLR3) or retinoic acid-inducible gene I (RIG-I) like receptors (RLRs) in mammalian cells. Both RNA silencing and IFN response are triggered by dsRNAs. However, the relationship between these two pathways has remained unclear. Labor ...[more]