Pleural effusion during weaning from mechanical ventilation: a prospective observational multicenter study.

ABSTRACT: BACKGROUND:Pleural effusion is common during invasive mechanical ventilation, but its role during weaning is unclear. We aimed at assessing the prevalence and risk factors for pleural effusion at initiation of weaning. We also assessed its impact on weaning outcomes and its evolution in patients with difficult weaning. METHODS:We performed a prospective multicenter study in five intensive care units in France. Two hundred and forty-nine patients were explored using ultrasonography. Presence of moderate-to-large pleural effusion (defined as a maximal interpleural distance???15 mm) was assessed at weaning start and during difficult weaning. RESULTS:Seventy-three (29%) patients failed weaning, including 46 (18%) who failed the first spontaneous breathing trial (SBT) and 39 (16%) who failed extubation. Moderate-to-large pleural effusion was detected in 81 (33%) patients at weaning start. Moderate-to-large pleural effusion was associated with more failures of the first SBT [27 (33%) vs. 19 (11%), p?

SUBMITTER: Razazi K 

PROVIDER: S-EPMC6211142 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature