Ontology highlight
ABSTRACT:
SUBMITTER: Lin H
PROVIDER: S-EPMC6215392 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Lin Huawen H Guo Suyang S Dutcher Susan K SK
Journal of cell science 20181026 20
Mutations in transition zone genes change the composition of the ciliary proteome. We isolated new mutations in <i>RPGRIP1L</i> (denotated as <i>RPG1</i> in algae) that affect the localization of the transition zone protein NPHP4 in the model organism <i>Chlamydomonas reinhardtii</i> NPHP4 localization is not affected in multiple new intraflagellar transport (IFT) mutants. We compared the proteome of cilia from wild-type and mutants that affect the transition zone (<i>RPGRIP1L</i>) or IFT (<i>IF ...[more]