Ontology highlight
ABSTRACT:
SUBMITTER: Jacquelot N
PROVIDER: S-EPMC6215820 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Jacquelot Nicolas N Duong Connie P M CPM Belz Gabrielle T GT Zitvogel Laurence L
Frontiers in immunology 20181029
The tumor microenvironment is highly heterogeneous. It is composed of a diverse array of immune cells that are recruited continuously into lesions. They are guided into the tumor through interactions between chemokines and their receptors. A variety of chemokine receptors are expressed on the surface of both tumor and immune cells rendering them sensitive to multiple stimuli that can subsequently influence their migration and function. These features significantly impact tumor fate and are criti ...[more]