Ontology highlight
ABSTRACT:
SUBMITTER: Pardo-Figuerez M
PROVIDER: S-EPMC6217525 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Pardo-Figuerez Maria M Martin Neil R W NRW Player Darren J DJ Roach Paul P Christie Steven D R SDR Capel Andrew J AJ Lewis Mark P MP
ACS omega 20181001 10
Conventional in vitro cultures are useful to represent simplistic neuronal behavior; however, the lack of organization results in random neurite spreading. To overcome this problem, control over the directionality of SH-SY5Y cells was attained, utilizing photolithography to pattern the cell-repulsive anionic brush poly(potassium 3-sulfopropyl methacrylate) (PKSPMA) into tracks of 20, 40, 80, and 100 μm width. These data validate the use of PKSPMA brush coatings for a long-term culture of the SH- ...[more]