Genetic Diversity of Noroviruses Circulating in a Pediatric Cohort in Bangladesh.
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ABSTRACT:
SUBMITTER: Nelson MI
PROVIDER: S-EPMC6217719 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
Genetic Diversity of Noroviruses Circulating in a Pediatric Cohort in Bangladesh.
Nelson Martha I MI Mahfuz Mustafa M Chhabra Preeti P Haque Rashidul R Seidman Jessica C JC Hossain Iqbal I McGrath Monica M Ahmed A M Shamsir AMS Knobler Stacey S Vinjé Jan J Ahmed Tahmeed T
The Journal of infectious diseases 20181101 12
Noroviruses are a leading cause of diarrhea in children aged <5 years worldwide. We genotyped 88 viruses collected by active surveillance in a birth cohort of children <2 years of age in Dhaka, Bangladesh, during 2010-2013. Twenty-five of 31 (81%) established GI and GII genotypes were detected, with GII.4 as the predominant genotype (20%). Our results show that children in Bangladesh are infected with a great diversity of norovirus strains. Reinfections are common, but not with closely related g ...[more]
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