Ontology highlight
ABSTRACT:
SUBMITTER: Rodrigues da Silva M
PROVIDER: S-EPMC6218022 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Rodrigues da Silva Marcia M Schapochnik Adriana A Peres Leal Mayara M Esteves Janete J Bichels Hebeda Cristina C Sandri Silvana S Pavani Christiane C Ratto Tempestini Horliana Anna Carolina AC Farsky Sandra H P SHP Lino-Dos-Santos-Franco Adriana A
PloS one 20181105 11
Paraquat (PQ) is one of the most widely employed herbicides that is used worldwide and it causes severe toxic effects in humans and animals. A PQ exposition can lead to pulmonary fibrosis (PF) and the mechanisms seem to be linked to oxidative stress, although other pathways have been suggested. Antioxidants can be useful as a therapy, although interventions with this kind of system are still controversial. Hence, this study has investigated the role of ascorbic acid (vitamin C) post-treatment on ...[more]