Ontology highlight
ABSTRACT:
SUBMITTER: Hanseeuw BJ
PROVIDER: S-EPMC6219621 | biostudies-literature | 2018 Oct
REPOSITORIES: biostudies-literature
Alzheimer's & dementia : the journal of the Alzheimer's Association 20180521 10
<h4>Introduction</h4>Amyloid positron emission tomography (PET) data are commonly expressed as binary measures of cortical deposition. However, not all individuals with high cortical amyloid will experience rapid cognitive decline. Motivated by postmortem data, we evaluated a three-stage PET classification: low cortical; high cortical, low striatal; and high cortical, high striatal amyloid; hypothesizing this model could better reflect Alzheimer's dementia progression than a model based only on ...[more]