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Mean level of positive affect moderates associations between volatility in positive affect, mental health, and alcohol consumption among mothers.

ABSTRACT: Affective volatility (i.e., variability) is typically conceptualized as a marker of poor mental and behavioral health. The current research challenges this notion. Among individuals who typically experience low positive affect (PA), vacillation between bouts of joy and marked anhedonia may be associated with better behavioral health relative to a restricted range of PA experience. We therefore tested the hypothesis that mean levels of PA captured via an 8-day intensive repeated Ecological Momentary Assessment (EMA) would moderate the association of EMA-measured PA variability with behavioral health measured at intake among working mothers (N = 202) with young children-a population at risk for experiencing repeated stress- and reward-induced PA changes. Mixed-effects location scale modeling parsed variance in PA mean and variability, which were used in subject-level regression models of associations with depressive symptoms, anxiety, and alcohol use. PA mean moderated the associations of PA variability with depressive symptoms (Interaction: ? = .20, p = .02) and alcohol consumption frequency (Interaction: ? = .22, p = .02). PA variability and depressive symptom and alcohol consumption levels were positively associated at higher PA mean levels, whereas PA variability was inversely associated with depressive symptom and alcohol consumption at low mean PA. PA Mean × Variability Interactions were not significant for anxiety and binge drinking. We conclude that (a) intensive longitudinal modeling of Affect Mean × Variability Interaction effects may provide incremental information in psychopathology research; (b) PA volatility does not unilaterally indicate poor behavioral health; and (c) a nuanced perspective on the role of PA volatility may benefit clinical services for working mothers. (PsycINFO Database Record (c) 2018 APA, all rights reserved).

SUBMITTER: Maher JP

PROVIDER: S-EPMC6219753 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Mean level of positive affect moderates associations between volatility in positive affect, mental health, and alcohol consumption among mothers.

Maher Jaclyn P JP Ra Chaelin K CK Leventhal Adam M AM Hedeker Donald D Huh Jimi J Chou Chih-Ping CP Dunton Genevieve F GF

Journal of abnormal psychology 20180917 7

Affective volatility (i.e., variability) is typically conceptualized as a marker of poor mental and behavioral health. The current research challenges this notion. Among individuals who typically experience low positive affect (PA), vacillation between bouts of joy and marked anhedonia may be associated with better behavioral health relative to a restricted range of PA experience. We therefore tested the hypothesis that mean levels of PA captured via an 8-day intensive repeated Ecological Moment ...[more]

PMID: 30221951

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Project description:BackgroundWe investigated the associations of alcohol with percentage of epithelium, stroma, fibroglandular tissue (epithelium + stroma), and fat in benign breast biopsy samples.MethodsWe included 857 cancer-free women with biopsy-confirmed benign breast disease within the Nurses' Health Study (NHS) and NHSII cohorts. Percentage of each tissue was measured on whole slide images using a deep-learning algorithm and then log-transformed. Alcohol consumption (recent and cumulative average) was assessed with semi-quantitative food frequency questionnaires. Regression estimates were adjusted for known breast cancer risk factors. All tests were 2-sided.ResultsAlcohol was inversely associated with % of stroma and fibroglandular tissue (recent ≥ 22 g/day vs. none: stroma: β = - 0.08, 95% Confidence Interval [CI] - 0.13; - 0.03; fibroglandular: β = - 0.08, 95% CI - 0.13; - 0.04; cumulative ≥ 22 g/day vs. none: stroma: β = - 0.08, 95% CI - 0.13; - 0.02; fibroglandular: β = - 0.09, 95% CI - 0.14; - 0.04) and positively associated with fat % (recent ≥ 22 g/day vs. none: β = 0.30, 95% CI 0.03; 0.57; cumulative ≥ 22 g/day vs. none: β = 0.32, 95% CI 0.04; 0.61). In stratified analysis, alcohol consumption was not associated with tissue measures in premenopausal women. In postmenopausal women, cumulative alcohol use was inversely associated with % of stroma and fibroglandular tissue and positively associated with fat % (≥ 22 g/day vs. none: stroma: β = - 0.16, 95% CI - 0.28; - 0.07; fibroglandular: β = - 0.18, 95% CI - 0.28; - 0.07; fat: β = 0.61, 95% CI 0.01; 1.22), with similar results for recent alcohol use.ConclusionOur findings suggest that alcohol consumption is associated with smaller % of stroma and fibroglandular tissue and a greater % of fat in postmenopausal women. Future studies are warranted to confirm our findings and to elucidate the underlying biological mechanisms.

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Mean level of positive affect moderates associations between volatility in positive affect, mental health, and alcohol consumption among mothers.

Publications

Mean level of positive affect moderates associations between volatility in positive affect, mental health, and alcohol consumption among mothers.

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