Ontology highlight
ABSTRACT:
SUBMITTER: Dyson G
PROVIDER: S-EPMC6220145 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Dyson Greg G Farran Batoul B Bolton Susan S Craig Douglas B DB Dombkowski Alan A Beebe-Dimmer Jennifer L JL Powell Isaac J IJ Podgorski Izabela I Heilbrun Lance K LK Bock Cathryn H CH
American journal of cancer research 20181001 10
MicroRNAs (miRNAs) constitute short non-coding RNAs that can post-transcriptionally modulate the expression of many oncogenes and tumor suppressor genes engaged in key cellular processes. Deregulated serum miRNA signatures have been detected in various solid cancers including prostate cancer, suggesting that circulating miRNAs could function as non-invasive biomarkers of tumor emergence and progression. To determine whether serum miRNA expression levels are different between patients with aggres ...[more]