Sex chromosome trisomies are not associated with atypical lateralization for language.

ABSTRACT:

Aim

To test the hypothesis that sex chromosome trisomies (SCTs) are associated with reduced left lateralization for language.

Method

Using a cross-sectional design, language laterality was measured during an animation description task using functional transcranial Doppler ultrasonography. Data were available for 75 children with an SCT (47,XXX females [n=26], 47,XXY males [n=25], 47,XYY males [n=24]; mean age 11y 4mo [SD 3y 10mo]) and 132 comparison children with typical karyotypes (69 males, 63 females; mean age 9y 1mo [SD 1y 7mo]).

Results

Lateralization for language did not differ between the SCT and comparison groups, either in mean laterality index or relative frequency of each laterality category. There were no differences when splitting the group with an SCT by

SUBMITTER: Wilson AC 

PROVIDER: S-EPMC6220794 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature