Ontology highlight
ABSTRACT:
SUBMITTER: Fernandes MT
PROVIDER: S-EPMC6220897 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Fernandes Mariane Teodoro MT Adashek Jacob J JJ Barreto Carmelia Maria Noia CMN Spinosa Ana Cláudia Barbin ACB de Souza Gutierres Barbara B Lopes Gilberto G Del Giglio Auro A Aguiar Pedro Nazareth PN
Drugs in context 20181105
In the last 3 years, a novel class of targeted therapy has been approved for patients with hormone receptor-positive, human epidermal growth factor receptor 2-negative (HR+/HER2-) breast cancer. There are currently three approved agents, which are oral cyclin-dependent kinase 4/6 (CDK4/6) inhibitors. All of the approved drugs exhibit progression-free survival benefit when compared to standard of care and generally have less adverse events compared to traditional chemotherapeutic options. The tre ...[more]