Ontology highlight
ABSTRACT:
SUBMITTER: Ramamoorthy A
PROVIDER: S-EPMC6220929 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Ramamoorthy Anuradha A Knepper Todd C TC Merenda Christine C Mendoza Martin M McLeod Howard L HL Bull Jonca J Zhang Lei L Pacanowski Michael M
Clinical pharmacology and therapeutics 20180914 5
Race, ethnicity, sex, and age are demographic factors that can influence drug exposure and/or response, and can consequently affect treatment outcome. We evaluated demographic subgroup enrollment patterns in new therapeutic products approved by the US Food and Drug Administration (FDA) for the treatment of select cancers-breast, colorectal, lung, and prostate-that have comparative differences in morbidity and/or mortality among some demographic subgroups. In submissions of products approved betw ...[more]