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Case Report: Atypical Cutaneous Leishmaniasis in a Patient with Mixed Leishmania guyanensis and Leishmania amazonensis Infection.


ABSTRACT: The disseminated form of leishmaniasis is a serious and rare disease, being diagnosed in 2% of the cutaneous cases registered per year in Brazil. The main characteristic is the appearance of multiple pleomorphic lesions on the cutaneous surface. A 68-year-old male from the rural area of Tocantins, Brazil, presented atypical disseminated cutaneous leishmaniasis (ACL). The clinical course and histopathological and immunological findings presented a mixed pattern that hindered diagnosis and therapeutic management. Molecular typing revealed a mixed infection with Leishmania (V.) guyanensis and Leishmania (L.) amazonensis. Molecular identification of the agents responsible for ACL is important for adequate therapeutic planning, minimizing the possibility of sequellae that impact the quality of life of the patient.

SUBMITTER: Gosch CS 

PROVIDER: S-EPMC6221246 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Case Report: Atypical Cutaneous Leishmaniasis in a Patient with Mixed <i>Leishmania guyanensis</i> and <i>Leishmania amazonensis</i> Infection.

Gosch Carina Scolari CS   Resende Bruna Silva BS   Amorim Célia Bastos CB   Marques Cálita Pollyanna CP   Pereira Ledice Inacia de Araújo LIA   Pinto Sebastião Alves SA   Uliana Silvia Reni Bortolin SRB   Coelho Adriano Cappellazzo AC   Ribeiro-Dias Fátima F   Dorta Miriam Leandro ML  

The American journal of tropical medicine and hygiene 20181101 5


The disseminated form of leishmaniasis is a serious and rare disease, being diagnosed in 2% of the cutaneous cases registered per year in Brazil. The main characteristic is the appearance of multiple pleomorphic lesions on the cutaneous surface. A 68-year-old male from the rural area of Tocantins, Brazil, presented atypical disseminated cutaneous leishmaniasis (ACL). The clinical course and histopathological and immunological findings presented a mixed pattern that hindered diagnosis and therape  ...[more]

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