Dataset Information

Banxia Baizhu Tianma decoction for hyperlipidemia: Protocol for a systematic review and meta-analysis.

ABSTRACT:

Background

Hyperlipidemia is one of the most common metabolic diseases worldwide, as well as a leading risk factor for cardio-cerebrovascular diseases. Banxia Baizhu Tianma decoction (BBTD) is widely used for the treatment of hyperlipidemia in China, however, systematic review and meta-analysis regarding its efficacy and safety is lacking. The aim of this protocol of systematic review is to evaluate the effectiveness and safety of BBTD in the treatment of hyperlipidemia.

Methods

We will include the randomized controlled trials estimating the effectiveness and safety of BBTD in the treatment of hyperlipidemia. Data sources will include 5 English databases (PubMed, EMBASE, Cochrane Library, Web of Science, CINAHL) and 4 Chinese databases (CMB, CNKI, VIP, Wanfang database). The literature to be collected will be from the time when databases were established to September 2018. Efficacy will be accepted as the primary outcome, while blood lipid levels and adverse reactions as the secondary outcome. Study selection, data collection, risk of bias assessment, and evaluation of the quality of the evidence will be conducted by 2?×?2 different reviewers. Statistical syntheses will be conducted by using RevMan software V.5.3.

Results

This study will provide a high-quality evidence for BBTD on the treatment of hyperlipidemia from efficacy, serum lipid levels, and adverse reactions.

Conclusion

The result will provide a basis for judging whether BBTD is an effective intervention for the treatment of hyperlipidemia.

Prospero registration number

PROSPERO CRD 42018081359.

SUBMITTER: Cai H

PROVIDER: S-EPMC6221624 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Publications

Banxia Baizhu Tianma decoction for hyperlipidemia: Protocol for a systematic review and meta-analysis.

Cai Hairong H Guo Yongning Y Zhao Zicong Z Chen Yanhong Y Zhao Shuai S Chen Bojun B

Medicine 20181101 44

<h4>Background</h4>Hyperlipidemia is one of the most common metabolic diseases worldwide, as well as a leading risk factor for cardio-cerebrovascular diseases. Banxia Baizhu Tianma decoction (BBTD) is widely used for the treatment of hyperlipidemia in China, however, systematic review and meta-analysis regarding its efficacy and safety is lacking. The aim of this protocol of systematic review is to evaluate the effectiveness and safety of BBTD in the treatment of hyperlipidemia.<h4>Methods</h4>W ...[more]

PMID: 30383686

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Project description:BackgroundInsomnia is a widespread complaint in the general population. Wendan decoction has been widely applied in the treatment of primary insomnia. However, to our knowledge, there has been no systematic review or meta-analysis of randomized controlled trails regarding the effectiveness of this treatment. Here, we provide a protocol to evaluate the efficacy and safety of Wendan decoction for primary insomnia.Methods and analysisRelevant randomized controlled trials in 5 English databases [EMBASE, the Cochrane Central Register of Controlled Trials (Cochrane Library), PubMed, the Allied and Complementary Medicine Databases (AMED), and the Cumulative Index to Nursing and Allied Health Literature (CINAHL)], 4 Chinese databases [Chinese Biomedical Literature Database (CBM), Chinese Medical Current Content (CMCC), China National Knowledge Infrastructure (CNKI), and Wanfang Database] will be comprehensively searched by 2 researchers in October 2017. The therapeutic effects according to the Pittsburgh Sleep Quality Index (PSQI) will be accepted as the primary outcomes. We will use RevMan V.5.3 software as well to compute the data synthesis carefully when a metaanalysis is allowed.ResultsThis study will provide a high-quality synthesis of current evidence of Wendan decoction for primary insomnia from several aspects including PSQI, the total scores of the Insomnia Severity Index (ISI), syndrome according to standards for assessing Traditional Chinese medicine and adverse events.ConclusionThe conclusion of our systematic review will provide evidence to judge whether Wendan decoction is an effective intervention for patient with primary insomnia.Ethics and disseminationThe outcomes of this systematic review will offer implications of the use of Wendan decoction treatment for primary insomnia patients. This knowledge informing recommendations will be provided by researchers who are interested in the treatment of primary insomnia. The results of this study will be disseminated through presentation at a conference and publication of the data in a peer-reviewed journal.Prospero registration numberPROSPERO CRD 42017065664.

Dataset Information

Banxia Baizhu Tianma decoction for hyperlipidemia: Protocol for a systematic review and meta-analysis.

Background

Methods

Results

Conclusion

Prospero registration number

Publications

Banxia Baizhu Tianma decoction for hyperlipidemia: Protocol for a systematic review and meta-analysis.

Similar Datasets

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