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Grimon: graphical interface to visualize multi-omics networks.

ABSTRACT:

Summary

Rapid advances in high-throughput sequencing technologies have enabled more efficient acquisition of massive amount of multi-omics data. However, interpretation of the underlying relationships across multi-omics networks has not been fully succeeded, partly due to the lack of effective methods in visualization. To aid interpretation of the results from such multi-omics data, we here present Grimon (Graphical interface to visualize multi-omics networks), an R package that visualizes high-dimensional multi-layered data sets in three-dimensional parallel coordinates. Grimon enables users to intuitively and interactively explore their analyzed data, helping their understanding of multiple inter-layer connections embedded in high-dimensional complex data.

Availability and implementation

Grimon is freely available at https://github.com/mkanai/grimon as an R package with example omics data sets.

Supplementary information

Supplementary data are available at bioinformatics online.

SUBMITTER: Kanai M

PROVIDER: S-EPMC6223372 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Grimon: graphical interface to visualize multi-omics networks.

Kanai Masahiro M Maeda Yuichi Y Okada Yukinori Y

Bioinformatics (Oxford, England) 20181101 22

<h4>Summary</h4>Rapid advances in high-throughput sequencing technologies have enabled more efficient acquisition of massive amount of multi-omics data. However, interpretation of the underlying relationships across multi-omics networks has not been fully succeeded, partly due to the lack of effective methods in visualization. To aid interpretation of the results from such multi-omics data, we here present Grimon (Graphical interface to visualize multi-omics networks), an R package that visualiz ...[more]

PMID: 29931190

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