Ontology highlight
ABSTRACT:
SUBMITTER: Liang B
PROVIDER: S-EPMC6224317 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Neuron 20180927 3
The medial prefrontal cortex (mPFC) is important for social behavior, but the mechanisms by which mPFC neurons code real-time social exploration remain largely unknown. Here we utilized miniScopes to record calcium activities from hundreds of excitatory neurons in the mPFC while mice freely explored restrained social targets in the absence or presence of the psychedelic drug phencyclidine (PCP). We identified distinct and dynamic ON and OFF neural ensembles that displayed opposing activities to ...[more]