Dataset Information

Depression, depressive symptoms and treatments in women who have recently given birth: UK cohort study.

ABSTRACT:

Objectives

To investigate how depression is recognised in the year after child birth and treatment given in clinical practice.

Design

Cohort study based on UK primary care electronic health records.

Setting

Primary care.

Participants

Women who have given live birth between 2000 and 2013.

Outcomes

Prevalence of postnatal depression, depression diagnoses, depressive symptoms, antidepressant and non-pharmacological treatment within a year after birth.

Results

Of 206?517 women, 23?623 (11%) had a record of depressive diagnosis or symptoms in the year after delivery and more than one in eight women received antidepressant treatment. Recording and treatment peaked 6-8 weeks after delivery. Initiation of selective serotonin reuptake inhibitors (SSRI) treatment has become earlier in the more recent years. Thus, the initiation rate of SSRI treatment per 100 pregnancies (95%?CI) at 8 weeks were 2.6 (2.5 to 2.8) in 2000-2004, increasing to 3.0 (2.9 to 3.1) in 2005-2009 and 3.8 (3.6 to 3.9) in 2010-2013. The overall rate of initiation of SSRI within the year after delivery, however, has not changed noticeably. A third of the women had at least one record suggestive of depression at any time prior to delivery and of these one in four received SSRI treatment in the year after delivery.Younger women were most likely to have records of depression and depressive symptoms. (Relative risk for postnatal depression: age 15-19: 1.92 (1.76 to 2.10), age 20-24: 1.49 (1.39 to 1.59) versus age 30-34). The risk of depression, postnatal depression and depressive symptoms increased with increasing social deprivation.

Conclusions

More than 1 in 10 women had electronic health records indicating depression diagnoses or depressive symptoms within a year after delivery and more than one in eight women received antidepressant treatment in this period. Women aged below 30 and from the most deprived areas were at highest risk of depression and most likely to receive antidepressant treatment.

SUBMITTER: Petersen I

PROVIDER: S-EPMC6224756 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature

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Publications

Depression, depressive symptoms and treatments in women who have recently given birth: UK cohort study.

Petersen Irene I Peltola Tomi T Kaski Samuel S Walters Kate R KR Hardoon Sarah S

BMJ open 20181024 10

<h4>Objectives</h4>To investigate how depression is recognised in the year after child birth and treatment given in clinical practice.<h4>Design</h4>Cohort study based on UK primary care electronic health records.<h4>Setting</h4>Primary care.<h4>Participants</h4>Women who have given live birth between 2000 and 2013.<h4>Outcomes</h4>Prevalence of postnatal depression, depression diagnoses, depressive symptoms, antidepressant and non-pharmacological treatment within a year after birth.<h4>Results< ...[more]

PMID: 30361401

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Project description:BACKGROUND:Electronic cigarettes (ECs) are increasingly used for reducing or stopping smoking, with some studies showing positive outcomes. However, little is known about views on ECs during pregnancy or postpartum and previous studies have nearly all been conducted in the US and have methodological limitations, such as not distinguishing between smokers and ex/non-smokers. A greater understanding of this topic will help to inform both clinicians and EC interventions. We elicited views and experiences of ECs among UK pregnant or recently pregnant women. METHODS:We conducted semi-structured telephone interviews, using topic guides, with pregnant or recently pregnant women, who were current or recent ex-smokers. To ensure broad views of ECs were obtained, recruitment was from several geographical locations and via various avenues of recruitment. This included stop smoking services, antenatal and health visitor clinics, a pregnancy website and an informal network. Participants were 15 pregnant and 15 postpartum women, including nine current EC users, 11 ex-users, and 10 never-users. Five women who were interviewed in pregnancy were later interviewed in postpartum to explore if their views had changed. Audio data was transcribed verbatim and framework analysis was applied. RESULTS:Five main themes emerged: motivations for use (e.g., for stopping or reducing smoking), social stigma (e.g., avoiding use in public, preferring 'discrete' NRT), using the EC (e.g., mostly used at home); consumer aspects (e.g., limited advice available), and harm perceptions (e.g., viewed as less harmful than smoking; concerns about safety and addiction). CONCLUSIONS:ECs were viewed positively by some pregnant and postpartum women and seen as less harmful than smoking and useful as aids for reducing and stopping smoking. However, due to perceived social stigma, some women feel uncomfortable using ECs in public, especially during pregnancy, and had concerns about safety and nicotine dependence. Health professionals and designers of EC interventions need to provide women with up-to-date and consistent information and advice about safety and dependence, as well as considering the influence of social stigma.

Dataset Information

Depression, depressive symptoms and treatments in women who have recently given birth: UK cohort study.

Objectives

Design

Setting

Participants

Outcomes

Results

Conclusions

Publications

Depression, depressive symptoms and treatments in women who have recently given birth: UK cohort study.

Similar Datasets

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