Ontology highlight
ABSTRACT:
SUBMITTER: Capilla-Gonzalez V
PROVIDER: S-EPMC6224797 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Capilla-González Vivian V López-Beas Javier J Escacena Natalia N Aguilera Yolanda Y de la Cuesta Antonio A Ruiz-Salmerón Rafael R Martín Franz F Hmadcha Abdelkrim A Soria Bernat B
Molecular therapy : the journal of the American Society of Gene Therapy 20180816 11
Diabetes is a chronic metabolic disorder that affects 415 million people worldwide. This pathology is often associated with long-term complications, such as critical limb ischemia (CLI), which increases the risk of limb loss and mortality. Mesenchymal stromal cells (MSCs) represent a promising option for the treatment of diabetes complications. Although MSCs are widely used in autologous cell-based therapy, their effects may be influenced by the constant crosstalk between the graft and the host, ...[more]