Reassessing the role of the Escherichia coli CpxAR system in sensing surface contact.
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ABSTRACT:
SUBMITTER: Kimkes TEP
PROVIDER: S-EPMC6226299 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
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Reassessing the role of the Escherichia coli CpxAR system in sensing surface contact.
Kimkes Tom E P TEP Heinemann Matthias M
PloS one 20181109 11
For proper biofilm formation, bacteria must have mechanisms in place to sense adhesion to surfaces. In Escherichia coli, the CpxAR and RcsCDB systems have been reported to sense surfaces. The CpxAR system is widely considered to be responsible for sensing attachment, specifically to hydrophobic surfaces. Here, using both single-cell and population-level analyses, we confirm RcsCDB activation upon surface contact, but find that the CpxAR system is not activated, in contrast to what had earlier be ...[more]
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