Unknown

Dataset Information

0

Functional eubacteria species along with trans-domain gut inhabitants favour dysgenic diversity in oxalate stone disease.


ABSTRACT: Analyses across all three domains of life are necessary to advance our understanding of taxonomic dysbiosis in human diseases. In the present study, we assessed gut microbiota (eubacteria, archaea, and eukaryotes) of recurrent oxalate kidney stone suffers to explore the extent of trans-domain and functional species dysbiosis inside the gut. Trans-domain taxonomic composition, active oxalate metabolizer and butyrate-producing diversity were explored by utilizing frc-, but-, and buk- functional gene amplicon analysis. Operational taxonomic units (OTUs) level analyses confound with the observation that dysbiosis in gut microbiota is not just limited to eubacteria species, but also to other domains like archaea and eukaryotes. We found that some of healthy eubacterial population retained together with Oxalobacter formigenes and Lactobacillus plantarum colonization in disease condition (p?

SUBMITTER: Suryavanshi MV 

PROVIDER: S-EPMC6226508 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

altmetric image

Publications

Functional eubacteria species along with trans-domain gut inhabitants favour dysgenic diversity in oxalate stone disease.

Suryavanshi Mangesh V MV   Bhute Shrikant S SS   Gune Rahul P RP   Shouche Yogesh S YS  

Scientific reports 20181109 1


Analyses across all three domains of life are necessary to advance our understanding of taxonomic dysbiosis in human diseases. In the present study, we assessed gut microbiota (eubacteria, archaea, and eukaryotes) of recurrent oxalate kidney stone suffers to explore the extent of trans-domain and functional species dysbiosis inside the gut. Trans-domain taxonomic composition, active oxalate metabolizer and butyrate-producing diversity were explored by utilizing frc-, but-, and buk- functional ge  ...[more]

Similar Datasets

| S-EPMC6536642 | biostudies-literature
| S-EPMC7269359 | biostudies-literature
| S-EPMC9145590 | biostudies-literature
| S-EPMC5306211 | biostudies-literature
| S-EPMC10278359 | biostudies-literature
| S-EPMC8459966 | biostudies-literature
| S-EPMC8496971 | biostudies-literature
| S-EPMC10173728 | biostudies-literature
| S-EPMC5198277 | biostudies-literature