Ontology highlight
ABSTRACT:
SUBMITTER: Vaeteewoottacharn K
PROVIDER: S-EPMC6231245 | biostudies-literature | 2019 Feb
REPOSITORIES: biostudies-literature
Vaeteewoottacharn Kulthida K Kariya Ryusho R Pothipan Phattarin P Fujikawa Sawako S Pairojkul Chawalit C Waraasawapati Sakda S Kuwahara Kazuhiko K Wongkham Chaisiri C Wongkham Sopit S Okada Seiji S
Translational oncology 20181109 2
The involvement of chronic inflammation in cholangiocarcinoma (CCA) progression is well established. Cluster of differentiation 47 (CD47) is mutually expressed in various cancers and serves as a protective signal for phagocytic elimination. CD47 signaling blockage is a recent treatment strategy; however, little is known regarding CD47 in CCA. Therefore, the potential use of CD47 targeting in CCA was focused. CD47 was highly expressed in CCA compared to hepatocellular carcinoma (HCC). Disturbance ...[more]