Dataset Information

Association of coronary dominance with the severity of coronary artery disease: a cross-sectional study in Shaanxi Province, China.

ABSTRACT:

Objective

To investigate whether coronary artery dominance is associated with the severity of coronary artery disease (CAD).

Design

Cross-sectional study.

Setting

Single-centre.

Participants

Between July 2015 and February 2017, 1654 patients who underwent coronary angiography (CAG) were recruited into this cross-sectional study.

Measurement and methods

According to coronary dominance, patients were classified into left dominance (LD), right dominance (RD) and codominance (CD) based on the CAG results. Multiple linear regression analysis was performed to test the association between severity of CAD and coronary dominance.

Results

The total Gensini score was significantly higher in the RD group than in the left-CD group (42.3±33.6 vs 36.3±29.8; p=0.033). After adjusting for potential confounding factors, the results of multivariate linear regression showed that RD was associated with the severity of CAD (?=6.699, 95% CI 1.193 to 12.205, p=0.017).

Conclusions

The results suggest that right coronary dominance was associated with the severity of CAD.

SUBMITTER: Yan B

PROVIDER: S-EPMC6231567 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature

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Publications

Association of coronary dominance with the severity of coronary artery disease: a cross-sectional study in Shaanxi Province, China.

Yan Bin B Yang Jian J Fan Yajuan Y Zhao Binbin B Ma Qingyan Q Yang Lihong L Ma Xiancang X

BMJ open 20181108 11

<h4>Objective</h4>To investigate whether coronary artery dominance is associated with the severity of coronary artery disease (CAD).<h4>Design</h4>Cross-sectional study.<h4>Setting</h4>Single-centre.<h4>Participants</h4>Between July 2015 and February 2017, 1654 patients who underwent coronary angiography (CAG) were recruited into this cross-sectional study.<h4>Measurement and methods</h4>According to coronary dominance, patients were classified into left dominance (LD), right dominance (RD) and ...[more]

PMID: 30413496

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Project description:BackgroundThe main objective was to investigate the burden of birth defects among alive infants and explore the impact of maternal lifestyle during pregnancy on the burden of birth defects in Northwest China.MethodsA stratified multi-stage sampling method was used to study infants born during 2010-2013 (and their mothers) in Shaanxi province of Northwest China. Socio-demographic information was collected using a structured questionnaire, and medical records from the local hospitals were used to determine the final diagnosis of birth defects. Poisson regression analysis was performed to assess the association between maternal lifestyles during pregnancy and the burden of birth defects, while adjusting for potential confounders.ResultsWe sampled 29098 infants, of whom 629 (i.e. 216.17 per 10000) were observed to have congenital defects. Cardiovascular system defects (77.32 per 10000) were found to be the most common. Mothers who had ever consumed alcohol during pregnancy were found to have infants with a higher prevalence of some categories of birth defects, including nervous system (Prevalence Rate Ratio, PRR:14.67, 95% CI: 1.94, 110.92), cardiovascular system (PRR:3.22, 95% CI: 1.02, 10.16) and oral clefts (PRR:9.02, 95% CI: 2.08, 39.10) in contrast to infants of mothers without any alcohol consumption. Maternal passive smoking during pregnancy lead to the increased burden of malformations of eye, ear, face and neck (PRR:1.95, 95% CI: 1.15, 3.33), cardiovascular system (PRR:1.70, 95% CI: 1.25, 2.31) and respiratory system (PRR:9.94, 95% CI: 2.37, 41.76) in their newborns. Further, tea or coffee consumption during pregnancy was positively correlated with the burden of specific birth defects, such as cardiovascular system (PRR: 2.44, 95% CI: 1.33, 4.46) and genital organs (PRR:14.72, 95% CI: 1.87, 116.11) among infants.ConclusionsThe prevalence of birth defects was high in Shaanxi province of Northwest China. The unhealthy lifestyles of mothers during pregnancy may increase the prevalence of congenital malformations. These findings in future may have some important implications for prevention of birth defects in Northwest China.

Project description:OBJECTIVES:As a vulnerable group, the elders' oral health gained less attention, particularly the relationship between socioeconomic status (SES) and dental caries. This study aimed to assess the associations and to explore the effects of confounders on the associations in elderly people. DESIGN:Cross-sectional study. SETTINGS:3 neighbourhood committees and 3 village committees in Sichuan Province, China. PARTICIPANTS:744 people (362 men and 382 women) aged 65-74 years were included. OUTCOME MEASURES:Oral health outcomes included the decayed, missing and filled teeth (DMFT) index and its components. SES was assigned by educational level, household income and type of household. The bivariate association between the participants' characteristics and DMFT was analysed using non-parametric tests. Four logistic regression models were used to analyse the associations between SES and dental caries by regulating confounders. RESULTS:Poor oral health was observed in these participants. Bivariate analysis showed a significant association between SES and DMFT (p?0.05). Only adjusting gender, high educational level (adjusted (AOR)=0.34, 95%?CI 0.17 to 0.66), high household income (AOR=0.47, 95%?CI 0.41 to 0.77) were protective factors against dental caries, and living in agricultural families (AOR=1.86, 95%?CI 1.32 to 2.63) was risk factor (p?0.05). After adjusting other confounders, SES was partly related to the dental caries. Moreover, an interaction existed among SES indicators. CONCLUSIONS:SES is associated with dental caries, and older people with low SES have poor oral health. The associations were explained partly by diet, behaviour and awareness. Our results provide effective evidence in targeted policy-making and intervention measures and implicate that pertinence measures, economic assistance and medical insurance funds should be provided to older people of low SES. Furthermore, a follow-up design should attempt to confirm the causal relationship between SES and dental caries and evaluate the effect of intervention.

Dataset Information

Association of coronary dominance with the severity of coronary artery disease: a cross-sectional study in Shaanxi Province, China.

Objective

Design

Setting

Participants

Measurement and methods

Results

Conclusions

Publications

Association of coronary dominance with the severity of coronary artery disease: a cross-sectional study in Shaanxi Province, China.

Similar Datasets

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