Ontology highlight
ABSTRACT:
SUBMITTER: Parbhoo S
PROVIDER: S-EPMC6231902 | biostudies-literature | 2018
REPOSITORIES: biostudies-literature
Parbhoo Sonali S Gottesman Omer O Ross Andrew Slavin AS Komorowski Matthieu M Faisal Aldo A Bon Isabella I Roth Volker V Doshi-Velez Finale F
PloS one 20181112 11
Simulation-based approaches to disease progression allow us to make counterfactual predictions about the effects of an untried series of treatment choices. However, building accurate simulators of disease progression is challenging, limiting the utility of these approaches for real world treatment planning. In this work, we present a novel simulation-based reinforcement learning approach that mixes between models and kernel-based approaches to make its forward predictions. On two real world task ...[more]