The Influence of Donor to Recipient Size Matching on Kidney Transplant Outcomes.

ABSTRACT:

Background

Nephron endowment in renal transplantation is infrequently considered, but may have important implications for post kidney transplantation outcomes. In this population-cohort study, we analyzed the deceased-donor kidney transplant outcomes stratified by donor-to-recipient size ratios.

Methods

Data for all deceased-donor adult kidney transplantation recipients between 2003 and 2015 were extracted from the UK Transplant Registry. We used weight as a surrogate marker for kidney size and defined the following mismatch categories (donor weight/recipient weight × 100): less than 75% (small donor kidney), 75% to 125% (weight matched kidney), and greater than 125% (large donor kidney). Univariable and multivariable analyses were undertaken to assess the relationship betwe

SUBMITTER: Arshad A 

PROVIDER: S-EPMC6233665 | biostudies-literature | 2018 Oct

REPOSITORIES: biostudies-literature