Ontology highlight
ABSTRACT:
SUBMITTER: Pavon LF
PROVIDER: S-EPMC6234773 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Pavon Lorena Favaro LF Sibov Tatiana Tais TT de Souza Andrea Vieira AV da Cruz Edgar Ferreira EF Malheiros Suzana M F SMF Cabral Francisco Romero FR de Souza Jean Gabriel JG Boufleur Pamela P de Oliveira Daniela Mara DM de Toledo Silvia Regina Caminada SRC Marti Luciana C LC Malheiros Jackeline Moraes JM Paiva Fernando F FF Tannús Alberto A de Oliveira Sérgio Mascarenhas SM Chudzinski-Tavassi Ana Marisa AM de Paiva Neto Manoel A MA Cavalheiro Sérgio S
Stem cell research & therapy 20181109 1
<h4>Background</h4>Previous studies have demonstrated remarkable tropism of mesenchymal stem cells (MSCs) toward malignant gliomas, making these cells a potential vehicle for delivery of therapeutic agents to disseminated glioblastoma (GBM) cells. However, the potential contribution of MSCs to tumor progression is a matter of concern. It has been suggested that CD133<sup>+</sup> GBM stem cells secrete a variety of chemokines, including monocytes chemoattractant protein-1 (MCP-1/CCL2) and stromal ...[more]