MiR-1246 is upregulated and regulates lung cell apoptosis during heat stress in feedlot cattle.
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ABSTRACT:
SUBMITTER: Hu Y
PROVIDER: S-EPMC6237691 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Publications
MiR-1246 is upregulated and regulates lung cell apoptosis during heat stress in feedlot cattle.
Hu Yu Y Cai Ming-Chen MC Wang Ling L Zhang Ting-Huan TH Luo Zhong-Gang ZG Zhang Gong-Wei GW Zuo Fu-Yuan FY
Cell stress & chaperones 20180813 6
Globally, heat stress seriously threatens productivity of cattle. The objective of this study was to identify novel miRNAs that regulated heat stress in feedlot cattle. Experiment was conducted under heat stress and normal conditions. With profiling miRNAs of each feedlot cattle, our results showed the level of miR-1246 was significantly increased in these heat-stressed cattle (P < 0.05). Furthermore, by using bioinformatics analysis and luciferase reporter assays combined with qPCR and western ...[more]
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