Ontology highlight
ABSTRACT:
SUBMITTER: Roux BM
PROVIDER: S-EPMC6238657 | biostudies-literature | 2018 Nov
REPOSITORIES: biostudies-literature
Roux Brianna M BM Akar Banu B Zhou Wei W Stojkova Katerina K Barrera Beatriz B Brankov Jovan J Brey Eric M EM
Tissue engineering. Part A 20181012 21-22
Vascular networks provide nutrients, oxygen, and progenitor cells that are essential for bone function. It has been proposed that a preformed vascular network may enhance the performance of engineered bone. In this study vascular networks were generated from human umbilical vein endothelial cell and mesenchymal stem cell spheroids encapsulated in fibrin scaffolds, and the stability of preformed vascular networks and their effect on bone regeneration were assessed in an in vivo bone model. Under ...[more]